Increased trafficking
نویسندگان
چکیده
منابع مشابه
Structural Disorder Provides Increased Adaptability for Vesicle Trafficking Pathways
Vesicle trafficking systems play essential roles in the communication between the organelles of eukaryotic cells and also between cells and their environment. Endocytosis and the late secretory route are mediated by clathrin-coated vesicles, while the COat Protein I and II (COPI and COPII) routes stand for the bidirectional traffic between the ER and the Golgi apparatus. Despite similar fundame...
متن کاملIncreased T cell trafficking as adjunct therapy for HIV-1
Although antiretroviral drug therapy suppresses human immunodeficiency virus-type 1 (HIV-1) to undetectable levels in the blood of treated individuals, reservoirs of replication competent HIV-1 endure. Upon cessation of antiretroviral therapy, the reservoir usually allows outgrowth of virus and approaches to targeting the reservoir have had limited success. Ongoing cycles of viral replication i...
متن کاملhuman trafficking in central asia
human trafficking is one form of organized crime with 7 to 10 billion dollars profit next to drug and weapon trades. former soviet republics and eastern europe have become the newest sources of human trafficking, for europe and north america for the purpose of sexual exploitation .this article is a result in causes of human trafficking in central asian republic of the former soviet :union:.
متن کاملDiverting T helper cell trafficking through increased plasticity attenuates autoimmune encephalomyelitis.
Naive T helper cells differentiate into functionally distinct effector subsets that drive specialized immune responses. Recent studies indicate that some of the effector subsets have plasticity. Here, we used an EAE model and found that Th17 cells deficient in the transcription factor BCL11B upregulated the Th2-associated proteins GATA3 and IL-4 without decreasing RAR-related orphan receptor γ ...
متن کاملIncreased antigen presentation efficiency by coupling antigens to MHC class I trafficking signals.
Genetic modification of vaccines by linking the Ag to lysosomal or endosomal targeting signals has been used to route Ags into MHC class II processing compartments for improvement of CD4+ T cell responses. We report in this study that combining an N-terminal leader peptide with an MHC class I trafficking signal (MITD) attached to the C terminus of the Ag strongly improves the presentation of MH...
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ژورنال
عنوان ژورنال: Nature Reviews Cancer
سال: 2009
ISSN: 1474-175X,1474-1768
DOI: 10.1038/nrc2704